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5-Amino-1MQ

One of the few substances in this range that is not a peptide at all.

PropertyValue
TypeSmall molecule, not a peptide
TargetThe enzyme NNMT
Research fieldFat cells, energy balance, weight
Research statusPreclinical
FormPowder, also as a capsule

What it is

A small organic molecule that blocks the enzyme NNMT. That enzyme is active in fat cells and has a hand in how much NAD+ stays available inside the cell.

How it works

By blocking NNMT, the literature reports, more NAD+ remains for energy metabolism. Animal models have looked at fat cell size and at energy expenditure alongside this.

What the research shows

The evidence is preclinical and largely from mouse models. It is a younger field than the GLP-1 family and there are no controlled human studies.

Research status

Preclinical.

Practical

Because it is not a peptide, the usual peptide rules do not apply: as a small molecule it is considerably more stable and less heat sensitive.

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What this site is and is not
This site explains what the scientific literature says about peptides. It is not medical advice and not a set of instructions. The substances discussed here are research compounds: they are not approved for use in humans or animals. If you have a health question, see a doctor.

Updated 2026-10-03

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